Female infertility treatment / Top clinic in Germany, Friedrichshafen

Female infertility treatment

Annually approximately 5,000 of couples from 80 countries visit our clinic for a high-quality reproductive medicine services. Highly professional doctors of gynecological department of the Friedrichshafen Clinic provide successful conservative and minimally invasive treatment of various gynecological diseases. One oft he main specialisation of the department are assisted reproductive techniques (ART).

The department of Gynaecology in Germany is headed by Hans-Walter Vollert, Dr. scient. med, who has more than 25 years of professional experience in treatment of male and female infertility.

The fertility clinic at Clinical center of Friedrichshafen works closely with the university hospitals oft he region, providing female infertility treatment in full accordance with the latest scientific achievements.

Infertility (sterility) is a shock to most couples. It can be equally on the woman, as well as the man that it does not work with the children. Sterility treatment sometimes helps, but it is not always possible to find a treatable cause of infertility. Read about the reasons for infertility and how they can be resolved.

Pregnancy: complex process

The prevention discontinued, had regular sex and still not pregnant? Infertility is not always immediately to be considered, because getting pregnant is a complex process:

First, an egg must mature and meet with a fertile sperm cell. If both fuse together successfully, the fertilized egg cell (zygote) migrates through the fallopian tube to the uterus (uterus) and usually develops into the bastocyst in order to stabilize in the uterine lining (endometrium). All these steps succeed only if the correct hormones are released at the right time, the fertilized egg is healthy and anatomically both partners work well.

Since a sperm cell survives a maximum of five days in the woman's body, and the egg itself can only be fertilized for 24 hours, the couple only stays for a few days a month for their attempt. Knowing the fertile days is therefore very helpful if you want to get pregnant. Only if it does not work within a year with the children to witness, it could indicate an infertility, which must be clarified.

Frequency of infertility (sterility)

In Germany, depending on the source, about seven to 15 percent of all couples are unintentionally childless - which means that within one year, despite intensive efforts (intercourse twice a week), they were unable to father a child. However, it is rarely spoken about. Shame, guilt and social pressure ensure that infertility is still a taboo topic. It can therefore be assumed that actually many more couples are affected.

Forms of infertility

Infertility is not the same as infertility. Doctors distinguish between primary and secondary sterility in a fertility disorder:

Primary sterility

In spite of unprotected intercourse, primary infertility has not produced a child. Either the woman has never conceived or the man has never conceived a child. But there is a clear reason for childlessness.

Secondary sterility

Secondary sterility affects women or men who have become parents, but can not make it again. Such secondary sterility may arise, for example, from intermittent infections or surgery.

Idiopathic sterility

If no clear cause for childlessness is identified, it is called idiopathic sterility. Depending on the source, up to 30 percent of couples are unable to trigger infertility.

Infertility: find causes

Before you prematurely diagnose sterility, you must have tried it for a while. If you suspect infertility, contact a gynecologist or a urologist or andrologist (specialist in male medicine). After a thorough examination, referral to a reproductive medical center may be helpful.

The diagnosis of suspected infertility may include:

Intensive conversation about past illnesses, infections, operations, cycle disturbances, miscarriages, abortions, living conditions, partner relationship

Woman: gynecological examination, ultrasound, hormone examination, ovulation control (basal temperature curve, cycle monitoring), uterine (hysteroscopy) and laparoscopy

Man: spermiogram, physical examination of the sexual organs (testicular malformation, inflammation, varicose veins), hair and body, hormone examination, testicular biopsy.

Causes of infertility of the woman

In addition to factors that favor sterility in both sexes, such as obesity, nicotine, drugs, alcohol or stress, there are gender causes of female infertility.

Advanced age

Nowadays, couples decide to start a family later and later. What you have to keep in mind: From the age of 30, the probability of female infertility increases: Thus, the chance to successfully become pregnant at 75 within one year at 75 percent, at 35 years, the value drops to 66 percent. At 40, he is only 44 percent. The reason: the number and quality of oocytes are decreasing and it increases the likelihood of chromosome damage, miscarriage, complications and infertility. Therefore, women should not wait too long to have children.

Hormonal disorder

In about 30 to 40 percent of women, a hormonal disorder is responsible for childlessness. If the female hormone balance does not run smoothly, the following problems lead to infertility:

  • Woman produces too little or no ova
  • ovulation does not occur (anovulation)
  • Structure of the uterine lining for the implantation is missing
  • Consistency of the cervical mucus (in the cervix) makes the penetration of the egg cell difficult.

If the normal cycle is disturbed, prolonged, shortened (oligomenorrhoea) or complete absence of the menstrual bleeding (amenorrhea) may occur. Not only the sex hormones, such as estrogen, prolactin, gonadotropin and the yellow-body hormone progesterone may cause female infertility. Very often, the infertility of the woman is also triggered by the thyroid hormones.

While hyperthyroidism causes abortion, hyperthyroidism (hypothyroidism) confuses the hormones prolactin and luteinizing hormone, which can lead to ovulation problems. In addition, impaired insulin metabolism in diabetes also causes hormonal or infertility. Women who suffer from severe overweight (obesity) often have increased male hormone (testosterone) and estrogen levels, as well as underweight can negatively affect fertility. An endocrine disorder (polycystic ovary syndrome) should also be clarified. Occasionally tumors (prolactioma) trigger an increased release of prolactin in the brain and interfere with ovulation.

Organic causes

It happens that a hormonal disorder has an organic cause. Occasionally, however, a congenital malformation, surgery or disease triggers infertility. Women with sticky, overgrown or closed fallopian tubes have big problems getting pregnant. Triggers for organic causes can be:

  • Inflammation (ectopic inflammation, for example)
  • Infections (e.g., Chlamydia)
  • endometriosis
  • Adhesions after surgery
  • spiral
  • Ovarian cysts
  • Benign tumors of the uterus (fibroids)
  • Hormone-producing tumors

Immunological sterility

Sometimes the immune system is to blame for infertility. In this case, women produce antibodies that are directed against the partner's own egg or sperm cells, bind them to and block cells that are considered foreign. Successful fertilization is no longer possible.

Causes of female infertility

About 80% of female sterility (infertility) cases are due to the following reasons:

  • Advanced age: After the age of 35 fertility decreases and the probability to get pregnant after age of 40 is less than 20%
  • Tubal factor: If the fallopian tubes were injured in some way
  • Endometriosis
  • Fibroids
  • Venereal diseases
  • Polycystic ovary syndrome
  • Chronic diseases, such as diabetes, cancer, thyroid disease, asthma or depression
  • Taking specific medications, such as antidepressants
Female infertility treatment

Hormonal balance is very important for the fertility status. Hormonal malfunctions can lead to disturbances in oocyte maturation, the absence of ovulation and to inadequate luteal formation. Frequently elevated levels of male hormones (androgens) are associated with ovarian cysts, which is number 1 cause of female infertility.

The fallopian tubes are the "conveyor " for the sperm to the egg. They also transport the fertilized egg into the uterus cavity. If the fallopian tubes are glued or otherwise closed, the transport of the egg can be difficult or completely impossible. Reasons may be, for example, inflammation process or previous ectopic pregnancies, as well as surgery or a spontaneous overgrowth of the uterine lining outside the uterus (endometriosis). Usually a short laparoscopic or laser surgery helps to unblock the fallopian tubes and make the pregnancy possible.

The cervix is ​​the narrowest point for sperm towards the egg. In case of scarring process (e.g. after surgery), closures or inflammation, the fertilization of the egg can be hindered. Also fibroids in the womb are sometimes the reason for holding to infertility or miscarriage.

Antibodies to egg or sperm as a reason of female infertility: The reason for such a disorder is the appearance of sperm-coating antibodies in the organism. Such components block the move of sperm cells. As a result they cannot reach the egg for fertilization. Such antibodies can appear in uterine cervix or in tubes.

Immunologic infertility requires specific diagnostics and treatment. Right after sexual intercourse the doctor takes the post-coital test. This test helps to detect sperm-coating antibodies that indicate sterility.

The treatment for immunologic infertility is correcting the immunological status of the organism that helps to lower the production of antibodies. Such treatment includes the intake of immunosuppressors.

Other causes of female infertility: Besides under- and overweight, large changes in weight in a short time, extreme physical stress, thyroid disorders, tumors (extremely rare), medications and stress can disrupt the hormonal balance and lead to female infertility. If you cannot get pregnant for more that 1 year of attempts, special tests should be performed in ordert o find out the reason of infertility.

The diagnostics of female infertility

Female infertility treatment

Infertility is rather hard to diagnose. Even longtime inability to get pregnant doesn’t point at it. In order to define the female sterility, a patient needs to go through the complex of diagnostic procedures. The greatest result of such diagnostic research and treatment is pregnancy that will be monitored up to the act of delivery. The major diagnostic methods for female infertility include:

  • Physical examination and ultrasound
  • Cycle observation
  • Hormone tests
  • Special ultrasound examination
  • Laparoscopy
  • Hysteroscopy
  • Investigation after intercourse
  • Polar body diagnosis (to rule out the genetic disorders)

The sterility can have three forms: severe, moderate and mild. Each case of infertility can be treated at fertility clinics through modern IVF treatment techniques.

IVF success rate in treatment of female infertility

If the surgical or conservative methods proved to be inefficient, the modern techniques of assisted reproductive medicine helps to treat female infertility. The facts are better than words: more than 110,000 children were born with the help of IVF or artificial insemination, performed at our clinic.

Artificial insemination

The artificial insemination is a treatment in which a suitable sperm of a male partner, which was previously prepared in the laboratory, is injected into a woman's uterus, to increase the potential of the sperm and the possibilities of fertilization of an egg. On this you can shorten the distance between the egg and sperm cells, so that they meet faster. The cost of artificial insemination is about 3 000 euro.

In Vitro Fertilisation (IVF)

The in vitro fertilization (IVF) is the union of an egg with a sperm in a laboratory tube with the aim to obtain a fertilized embryo, which can then be transferred to the uterus. The fertilization of the eggs can be effected by the conventional IVF technique or by intracytoplasmic injection (ICSI) with sperm. Cost of the in-vitro fertilization at our clinic makes up about 7 000 euro (pro cycle).

IVF PLUS (FIV + PGS)

IVF Plus is the combination of IVF (in vitro fertilization) and PGS (Preimplantation Genetic Screening). This procedure helps to achieve especially favorable conditions for an embryo and to ensure health and safety of the future child. The clinical testings have shown that the chromosome analysis helps to achieve the higher success rate of pregnancies per transfer.

If you have faced the problem of infertility, the specialists of the Friedrichshafen Center will do their best to help you. We will provide you with innovational treatment methods that dramatically increase chances to become happy parents of a healthy child.

Female infertility treatment

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Medical Staff

MD PD H.-W. Vollert

MD PD H.-W. Vollert
Head of the Gynaecology Department

MD Bernd König

MD Bernd König
Head physician assistant

MD Ina Seidenspinner

MD Ina Seidenspinner
Senior physician

MD Karin Roth

MD Karin Roth
Senior physician

MD Alexandru Armion

MD Alexandru Armion
Senior physician

Daniela Reichert

Daniela Reichert
Medical secretary

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IVF treatment

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